General requirements for applicants:

• The candidate has Romanian citizenship or citizenship of other Member States of the European Union or of the European Economic Area and residence in Romania;
• The candidate should not have more than 8 years after the date of PhD defense;
• The applicants must be fluent in English and have excellent teamwork and communication skills;
• Candidate has full working capacity;
• The candidate should be in a state of health appropriate for the applied position;
• The applicant is medically fit;

Specific requirements of the applicants:

The candidate must have a bachelor's and master's degree and have successfully passed a PhD defense.

• Background in Biophysics/ Biochemistry / Chemistry / Structural Biology /Molecular Biology/ Molecular spectroscopy; 
• A strong background in NMR spectroscopy (1D and 2D experiments, pulse sequences and product operators for spin dynamics) is desirable. Experience in liquid-state hyperpolarized NMR would be highly desirable.
• Skills in analyzing cell lysates and free radicals;
• The candidate must have willingness to travel within the country and abroad;
• Practical computer skills (Word, Excel, Power Point, Origin) are required.

The candidate will develop and implement NMR methods, adapt hardware and protocols to perform NMR experiments in vitro and in cells. Specific applications for the study of the metabolism of healthy and cancer cells will be carried out in close collaboration with the research groups at Extreme Light Infrastructure - Nuclear Physics (ELI-NP), in particular with the group of Prof. Paul Vasos.

The application dossier must contain the documents stipulated in Art. 15 para. (6) of Law no. 319/2003 on the Statute of Research and Development Personnel, namely:

• The candidate's application, requesting to apply for the postdoctoral fellowship, dated and signed by the candidate, approved by the Director of the institute and registered within the legal deadline;  
• Copies of the identity card or passport; 
• Diploma’s copies (bachelor, master and proof of Ph.D. defense);
• CV including full details of previous training and research experience to date;  
• Publication record;
• Cover letter explaining why the candidate wants to join the team and what will bring to the 
  project;
• Health certificate clearly stating the state of health;
• Criminal record or a statement there is no criminal convictions.

*Note: in the case of the doctor diploma obtained outside Romania, the equivalent certificate obtained by the authorized Romanian institution is required on employment date.

   Selection:

• Analysis of the candidate's dossier (eliminatory). The results of the selection of the competition files are displayed with the mention 'admitted' or 'rejected';

• Interview: grade from 1 to 10.

• Candidates will be ranked according to the interview score.

Topics:

- Biomolecular markers and NMR methods ( 1H, 13C, 15N);

- Free radicals for biomarkers – source of spin polarization

References:

1) P.J.Hore, J.R. Jones, and S. Wimperis, "NMR: the toolkit", second edition, Oxford University Press, 2015.

2) J. Cavanagh et al., "Protein NMR Spectroscopy, Principles and Practice", second edition, Academic Press 2006.

3) A. Sadet, et al. (2020). Chapter 20. Long-lived Coherences. 10.1039/9781788019972-00371, in "Long-lived nuclear spin order", edited by G. Pileio, Royal Soc. Chem. 2020.

4) T. Asavei et al., “Laser-driven radiation: Biomarkers for molecular imaging of high dose-rate effects,” Medical Physics, vol. 46, no. 10, pp. e726–e734, 2019,doi: 10.1002/mp.13741.

5) Kurhanewicz et al., " Analysis of Cancer Metabolism by Imaging Hyperpolarized Nuclei: Prospects for Translation to Clinical Research", Neoplasia, 13, 2, 2011, https://doi.org/10.1593/neo.101102

Details are found at https://icoscdn.ro, Public information/vacancies (https://icoscdn.ro/index.php/en/public-information/vacancies),https://euraxess.ec.europa.eu/,  https://jobs.research.gov.ro/, or at HR department of ICOS, telefon +40 2131 679 00.

            Please send applications to simona.nica@icoscdn.ro, cc to paul.vasos@icub.unibuc.ro and arnaud.comment@gmail.com including the following: - a CV including full details of previous training and research experience to date; - a publication record; - the  names and contact details of two academic referees; - a cover letter  explaining why you want to join our team and what you will bring to the 
project.