Project description

We offer one research position to collaborate in an European research project:

Project T3SS: “Placing the T3SS effector-network paradigm within a systems level understanding of in vivo infection”. Funded by Wellcome Trust. Ends on May 2027. 

This research project is in collaboration with Gady Frankel group from Imperial College (London, UK) and Jyoti S. Choudhary from Institute of Cancer Research (London, UK). The main goal of the project includes exploring the bacterial “effector network” paradigm (effectors are bacterial proteins injected in an infected host), constructing computational models to predict infection outcomes, and studying signal transduction from effector injection into intestinal epithelial cells to immune responses. We (LIA group) are developing AI models (graph neural networks, graph transformers) to extract knowledge from the network of effectors that interact with the proteins of the infected host. 

Our previous results in this research line have been published in Science journal: 

https://www.science.org/doi/10.1126/science.abc9531

Brief description of the Centre/Research Group

Laboratorio de Inteligencia Artificial (LIA-UPM) www.lia.upm.es  is an interdisciplinary research group in UPM formed by researchers and professors working in Systems and Synthetic Biology, DNA Computing, and Artificial Intelligence applied in biomedicine and microbiology.

Documents to be submitted

CV, letter of motivation, letter of references. 

Deadline: April 30, 2025.

Email: arpaton@fi.upm.es (Alfonso Rodríguez-Patón)