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  • Switzerland

PhD in Advanced Mass Spectrometry for tRNA Structural Analysis

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15 Apr 2025

Job Information

Organisation/Company
University of Geneva
Department
Pharmaceutical Sciences
Research Field
Chemistry » Analytical chemistry
Chemistry » Biochemistry
Biological sciences » Other
Researcher Profile
First Stage Researcher (R1)
Positions
PhD Positions
Country
Switzerland
Application Deadline
Type of Contract
Temporary
Job Status
Full-time
Hours Per Week
40
Offer Starting Date
Is the job funded through the EU Research Framework Programme?
Not funded by a EU programme
Is the Job related to staff position within a Research Infrastructure?
No

Offer Description

Our group is committed to advancing mass spectrometry. We excel in 'native' mass spectrometry, revealing nucleic acid structures and interactions with ligands and proteins. We are seeking a bright PhD candidate to join our dynamic research team. The successful candidate will develop and apply innovative native mass spectrometry techniques to investigate how covalent modifications influence the secondary and tertiary structures of tRNAs. This research encompasses fundamental studies on temperature-variable electrospray mass spectrometry (MS) and ion mobility spectrometry, integrated with native top-down fragmentation methods. The objective is to elucidate the impact of natural tRNA modifications on their biophysical and biochemical stability. This work aims to provide new insights for data interpretation and contribute significantly to our understanding of RNA biology.

Where to apply

E-mail
valerie.gabelica@unige.ch

Requirements

Research Field
Chemistry
Education Level
Master Degree or equivalent
Research Field
Biological sciences
Education Level
Master Degree or equivalent
Research Field
Pharmacological sciences
Education Level
Master Degree or equivalent
Skills/Qualifications
  • Understand key concepts and relevant knowledge in molecular sciences and analytical sciences.
  • At least 6 months research experience gained during the masters studies or equivalent.
  • Ability to think critically about a scientific subject.
  • Ability to communicate fluently in English (oral, written) and synthesize thoughts.
  • Understand the value of collaborative work.
  • Curious to learn and open-minded.
Languages
ENGLISH
Level
Excellent
Internal Application form(s) needed
PhD application form - Euraxess.pdf
English
(419.47 KB - PDF)
Download

Additional Information

Benefits

The gross salary per year will be in the range of 55'000 CHF. The exact net salary is dependent on local tax and social and health insurance regulations and will be confirmed upon appointment. 

Selection process

Candidates should submit a CV, two references (name, affiliation and email of people acquainted with your academic performance and/or past projects). In lieu of cover letter, please submit the internal application form, which contains open questions. Without the form, your application will not be considered.

Applications will be reviewed from May 2nd to May 15th. Interviews can be organized via zoom or on site, or at the ASMS conference. The starting date is flexible between July and October 2025. 

Work Location(s)

Number of offers available
1
Company/Institute
University of Geneva
Country
Switzerland
City
Geneva
Postal Code
1206
Street
Avenue de Champel 7
Geofield

Contact

City
Geneva
Website
Street
1 rue Michel-Servet
Postal Code
1211
E-Mail
valerie.gabelica@unige.ch

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