The study is aimed to evaluate the effects of intraovarian injection of autologous platelet-rich plasma (PRP) on the outcomes of orthotopic reimplantation of cryopreserved ovarian tissue (OTT), in terms of endocrine function recovery. The Patients who have cryopreserved their ovarian tissue at the Cryobanca of the IRCCS University Hospital of Bologna, in early menopause or with menstrual irregularities, who require OTT will be enrolled. The achievement of the objectives of the study will be assessed through a general medical examination during which we will look for any adverse events to the addition of PRP during the standard laparoscopic procedure through hormonal blood tests and ultrasound examination to evaluate the morphological characteristics of the ovary. The check-ups will start immediately after the replantation and will be repeated monthly, for a maximum duration of 6 months. The results will be used for scientific dissemination.